Protect the dolls. Popularized by fashion designer Conner Ives and using the language of ballroom culture to refer (affectionately) to trans women, this phrase urges all of us to care for—indeed, to put our bodies on the line for—the most vulnerable among us. In this issue, Contexts’ authors take up big social problems, from the current multi-front assault on queer and trans people to the opioid epidemic, urban segregation, and environmental racism, and they introduce us to the scholars, activists, and everyday people innovating and implementing big, often sociological solutions (including, in a special section, the DEI programs vilified by many on the political right).